What should be monitored after administering tPA?

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Monitoring neurological status after the administration of tPA (tissue Plasminogen Activator) is critically important because tPA is used to dissolve blood clots in patients with acute ischemic stroke. Following the administration of tPA, there is a risk of both reocclusion of the blood vessel and the potential for hemorrhagic transformation, which can significantly affect the patient’s neurological function.

Evaluating neurological status enables nurses and healthcare providers to detect any changes that may indicate complications such as intracerebral hemorrhage or recurrent ischemia. This assessment typically involves using scales like the NIH Stroke Scale (NIHSS), which helps quantify neurological deficits, allowing for timely intervention if any deterioration is observed.

While monitoring blood glucose levels, heart rate, and dietary intake is important in the overall management of stroke patients, they do not directly indicate the immediate effects and complications associated with tPA administration as effectively as assessing neurological status does. Therefore, ensuring close observation of neurological function is paramount in the post-administration phase of tPA treatment to provide optimal care and improve patient outcomes.

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