When administering mannitol IV every 3 hours, which parameters should be primarily monitored?

The correct answer emphasizes the importance of monitoring serum osmolality, cerebral perfusion pressure (CPP) goals, and fluid balance when administering mannitol intravenously. Mannitol is an osmotic diuretic commonly used to manage increased intracranial pressure (ICP) by reducing cerebral edema.

Monitoring serum osmolality is crucial because mannitol can significantly alter osmolar levels in the blood, leading to potential complications if not carefully managed. A proper balance ensures that the osmotic effects remain therapeutic while minimizing risks such as dehydration or overcorrection, which can result in rebound ICP.

Cerebral perfusion pressure is equally critical, as maintaining adequate CPP is vital for ensuring sufficient blood flow to the brain. This measurement helps assess whether the treatment is effectively ameliorating conditions associated with elevated ICP.

Fluid balance must also be closely observed due to the diuretic effect of mannitol. Excessive fluid loss can lead to dehydration and hypotension, while inadequate fluid loss may fail to address the intended reduction in ICP.

While monitoring blood glucose, electrolytes, kidney function, or vital signs like heart rate and blood pressure is important in various clinical contexts, they are not the primary focus in relation to mannitol administration, where os