Why are thrombolytics not suitable for certain patients?

Thrombolytics, also known as clot busters, are powerful medications used to dissolve blood clots that can cause strokes. However, their use is not appropriate for all patients due to significant risks associated with their administration, particularly the risk of hemorrhage. Certain conditions increase the likelihood of bleeding complications, such as having fragile blood vessels, recent surgery, or uncontrolled hypertension. In patients with these conditions, the potential benefits of thrombolytics may be outweighed by the risk of causing severe internal bleeding, which can lead to further complications or worsen the patient’s overall condition.

In this context, the choice regarding the risk of hemorrhage due to fragile blood vessels or high blood pressure directly addresses the core concern with thrombolytics in specific patient populations. The therapeutic decision to use thrombolytics involves careful consideration of the patient's overall clinical picture, including any contraindications that may increase the risk of adverse effects like hemorrhage.